Codon Wizard 1.1

Codon Wizard is a gene design and analysis tool that streamlines codon optimization and sequence cleanup for reliable expression across multiple hosts. Developed by AK Harald Schwalbe, it helps researchers adapt coding sequences to organism-specific codon usage while preserving protein function, improving translational efficiency, and minimizing problematic sequence motifs.

Key capabilities:

• Host-aware codon optimization using configurable codon usage preferences
• Reverse translation from protein sequences with customizable constraints
• Control over GC content, codon adaptation index (CAI), and rare-codon runs
• Automatic screening to reduce unwanted patterns such as certain restriction sites and repeats
• Clear visual summaries of codon usage and optimization metrics
• Batch processing and reusable presets for reproducible workflows
• Import and export in common sequence formats (for example, FASTA and GenBank)

Who it’s for:

• Molecular and synthetic biologists designing expression constructs
• Biotech and pharmaceutical teams optimizing heterologous expression
• Educators and students learning about codon usage and gene design

With an intuitive interface and flexible settings, Codon Wizard makes it easier to go from protein concept to expression-ready DNA sequences, accelerating design cycles and improving downstream cloning and expression outcomes.

Codon Wizard is developed by AK Harald Schwalbe. The most popular version of this product among our users is 1.1. The name of the program executable file is Codon Wizard.exe.

You can check Wizard Land, Driver Wizard, Spider Wizard and other related programs like NetZero Connection Wizard at the "download" section.